Plasmafabriek Sanquin

VariQuin

To prevent chicken pox in ‘at risk’ groups

Description

VariQuin is a medicine, produced from blood plasma and contains varicella zoster antibodies to prevent chicken pox in groups deemed to be at risk.

To prevent chicken pox in ‘at risk’ groups

Product information

VariQuin will not be available for a fairly long period of time due to production problems.

As there is no replacement product in the Netherlands and it concerns a serious indication, Sanquin has ensured that, with the permission of the Inspectorate for Health and Youth Care (IGJ), an equivalent alternative is available. This is VariZIG from SAOL therapeutics. The availability of this product is however limited, consequently Sanquin will only supply checked deliveries and will not honour any orders placed simply for stock purposes.

The VariZIG product is an equivalent product covering the same range of symptoms as VariQuin. A Dutch SPC is enclosed, this is a translation of the version approved in Canada. Refer to the enclosure for complete dosage advice.

  • When is VariQuin used?

    VariQuin can be administered to ‘at risk’ groups to prevent chicken pox.

    At risk groups include:

    • New-borns whose mothers develop chicken pox in the period five days before and up to two days after their birth.
    • People who have no or an inadequate immune system who have come into contact with someone who has chicken pox.
    • Premature babies, younger than 28 weeks of gestation or new-borns with a birth weight below 1,000 grams who have come into contact with someone who has chicken pox.
    • Premature babies who during their stay in hospital have come into contact with someone who has chicken pox.
    • Pregnant women, adults and geriatrics whose health is poor and have never had chicken pox themselves and have come into contact with someone who has chicken pox.

    Read more in the VariQuin leaflet (pdf).

  • How is VariQuin used?

    VariQuin is a solution for an injection. To prevent chicken pox, the patient can be administered an intramuscular injection of VariQuin.

  • The dosage of VariQuin?

    • New-born babies with a body weight of up to 2 kg: 1 ml;
    • People with a body weight of 2-10 kg: 1 vial of 2ml;
    • People with a body weight of 10-30 kg: 2 vials of 2ml;
    • People with a body weight of over 30 kg: 3 vials of 2ml.
  • Administering VariQuin

    To prevent chicken pox, the patient can be administered an intramuscular injection of VariQuin. This is slowly injected into the patient’s upper arm or buttock.

    • Remove the vial from the refrigerator and allow it to reach room temperature.
      It is a clear solution.
    • During the period of storage, slight turbidity or a small amount of precipitation may occur.
    • Dependent on the dosage, more than one vial may be used. 
    • The content of several vials can be mixed for administration to the patient.
    • The product should be suctioned into a sterile syringe.

      Read more in the VariQuin leaflet (pdf).
  • What are the side effects of VariQuin?

    VariQuin can cause side effects, in the same way as all other medicines. The patient may feel some pain or sensitivity at the site of the injection.

    In rare cases, the patient could develop a fever and/or a skin rash. Side effects include nausea, vomiting, low blood pressure, a rapid heartbeat and hypersensitivity reactions. 

    Read more in the VariQuin leaflet (pdf).

  • How is VariQuin stored?

    • out of reach and sight of children

    • in the refrigerator at 2 - 8 °C (therefore, do not freeze)

    • in the original packaging to protect it from the light

      Not to be used after the expiry date
      Do not use VariQuin after its expiry date. This is stipulated on the label (on the vial) and on the box.

      Disposal
      Patients can hand any used medicines over to a pharmacy. By not disposing of medicines via waste water or household waste, we are helping to protect the environment.

      Read more in the VariQuin leaflet (pdf).